West Virginia vs LSU Prediction: Baton Rouge Super Regional Preview
Last updated June 5, 2025

As the 2025 NCAA Baseball Tournament advances to the Super Regionals, a best-of-three series is set between the No. 6 LSU Tigers and the West Virginia Mountaineers. This matchup, starting on Saturday, June 7, at Alex Box Stadium in Baton Rouge, features two teams with very different paths to this stage. LSU, a perennial powerhouse, seeks a return to Omaha, while West Virginia aims to continue its impressive postseason journey under first-year head coach Steve Sabins. Continue reading to get our West Virginia vs LSU prediction as we continue making our college baseball predictions for this year's tournament.
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West Virginia vs LSU Super Regionals Preview
West Virginia (44–14) enters the Super Regionals after clinching the Big 12 regular-season title and sweeping through the Clemson Regional. The Mountaineers' success has been fueled by standout performances, particularly from pitcher Jack Kartsonas. Kartsonas is 6-3 with a 2.94 ERA and he delivered a solid start against Clemson to help upset the top seed in their regional group. Another great performance will be required from him to help topple another national seed this weekend.
LSU (46–15), under the guidance of head coach Jay Johnson, has demonstrated dominance throughout the season. The Tigers secured the Baton Rouge Regional with three wins in four games, including a 2-1 mark over fourth-seed Little Rock. Their offense is led by Ethan Frey, who has a team-best .359 batting average with 27 extra-base hits on the year. On the mound, LSU's pitching staff is anchored by Anthony Eyanson and Kade Anderson. Both pitchers have a combined record of 19-3 on the year. The Tigers' combination of potent offense and reliable pitching positions them as serious contenders in this series.
Betting Insights
In the current betting landscape, LSU is favored to win the College World Series with odds of +330, reflecting their strong season performance and historical success. Conversely, West Virginia is considered a long shot with odds of +6000, indicating the perceived disparity between the teams. In this series, LSU is a -430 favorite to go to Omaha, with West Virginia at +300.
For bettors, key considerations include:
- LSU's Home Advantage: Playing at Alex Box Stadium provides the Tigers with a significant edge, supported by a passionate fan base and familiarity with the field.
- Pitching Matchups: The effectiveness of West Virginia's staff against LSU's potent lineup will be crucial. Similarly, LSU's pitching depth may challenge the Mountaineers' offense.
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West Virginia vs LSU Super Regionals Prediction
Analyzing the teams' trajectories and current form, LSU appears to have the upper hand in this Super Regional series. Their balanced roster, combining offensive firepower with starting pitching depth, provides a comprehensive threat. While West Virginia's determination and standout performances have propelled them thus far, the challenges posed by injuries and the strength of their opponent may prove insurmountable and those making their betting picks on this series should back the Tigers to move forward.
Prediction: LSU to win the series 2–0, advancing to the College World Series.
