Louisville vs Coastal Carolina Prediction: 2025 College World Series Semifinals
Last updated June 18, 2025
The semifinals of the 2025 College World Series will begin on Wednesday, June 18, with a matchup between the Louisville Cardinals and Coastal Carolina Chanticleers. The Chanticleers enter this game on a massive winning streak and will look to eliminate Louisville to reach the final and get some much-needed rest beforehand. Here, we break down this matchup on the diamond and bring you our Louisville vs Coastal Carolina prediction before the semis get started.
Our Louisville vs Coastal Carolina Pick
- Pick: Coastal Carolina -2.5
- Confidence: ★★★☆☆
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Game Snapshot
- Matchup: Louisville Cardinals vs Coastal Carolina Chanticleers
- Date & Time: Wednesday, June 18, 2025, 2:00 p.m. ET
- Stadium: Charles Schwab Field, Omaha, NE
- Broadcast: ESPN
| Moneyline | Runline | Total | |
|---|---|---|---|
| Louisville | +180 | +2.5 (-140) | Over 11 (-115) |
| Coastal | -238 | -2.5 (+110) | Under 11 (-115) |
Key Storylines
Pitching Form
So far in this tournament, Coastal Carolina's pitching has been rock solid. They have allowed 3.0 runs per game to Arizona and Oregon State, looking especially impressive in their winner's bracket win over the Beavers. Louisville has looked strong on the bump for the most part as well, but they are facing a rest disadvantage having had to play one extra game to get to this stage. Those making college baseball picks for this game should keep that in mind before making any of their decisions.
Bullpen Usage
Bullpen usage is not a concern for Coastal Carolina at this point, as they had a day off on Tuesday to get everyone set for this matchup with the Cardinals. Louisville's bullpen, meanwhile, had to work six innings against Oregon State on Tuesday. In those six innings, they faced some jams consistently in the late innings and they will look to overcome all of that adversity by putting in a strong showing against the Chants this afternoon.
Recent Team Streaks
- Coastal Carolina has won 25 games in a row coming into this matchup, by far the longest active win streak in the country.
- Louisville has won two straight games after losing their CWS opener to Oregon State.
Betting Trends & H2H
These teams have played seven total games against each other all-time. Coastal Carolina has won six of those games, with the vast majority of them being played in Conway, SC, the home of the Chanticleers. However, these teams have not faced off since 2002, so you can throw the history between them out when handicapping this game.
Louisville vs Coastal Carolina Model Projection
Score Projection: Coastal Carolina 8 - Louisville 4
Win Probability: Coastal Carolina 78%, Louisville 22%
Final Thoughts
✅ The Chanticleers have a 25-game win streak going into this semifinal matchup.
Louisville clearly has pop in their lineup and a high ceiling when it comes to their pitching staff. But Coastal Carolina might be playing the best baseball of any team in the country right now. We will take the Chants to win convincingly here and to punch their ticket into the championship series of this year's Men's College World Series.
