Los Angeles Rams vs San Francisco 49ers 10/3/22 Predictions and Caesars Sportsbook Promo

October 3, 2022

12:15 AM ET Oct 4
Los Angeles Rams vs San Francisco 49ers
San Francisco 49ers -1.5

The San Francisco 49ers are set to host a game against the Los Angeles Rams at Levi's Stadium to close out Week 4 on Monday Night Football. This will be the 10th game between the two teams in the past five years.

Rams coach Sean McVay will look to WR Cooper Kupp and RB Cam Akers to keep their offense moving in this division game. Meanwhile, 49ers coach Kyle Shanahan will try to return to the winning path with the help of Jimmy Garoppolo, who has 365 passing yards and two touchdowns since taking over for Trey Lance.

According to Caesars Sportsbook, the San Francisco 49ers are a 1.5-point favorite for this upcoming game. You can get up to $1,250 of your stake back in free bets if you lose your first wager at Caesars Sportsbook, by making a minimum first deposit of $10 after signing up with the promo code listed below.

Why bet on the San Francisco 49ers?

✅ San Francisco's defense holds the opposing offense to only 227.0 yards per game, good for second in the league.
✅ San Francisco is rushing for 151.0 yards per game, which puts the team as the sixth-best rushing team in the league.
✅ From the past three games, San Francisco's defense has allowed their opponents to score 12.3 points per game.

TeamsLos Angeles Rams vs San Francisco 49ers
WhenMonday, October 3, at 8:15 p.m. ET
VenueLevi’s Stadium, Santa Clara, CA
Betting PicksSan Francisco 49ers -1.5 (-110)

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Los Angeles Rams vs San Francisco 49ers

Los Angeles Rams

Although the Rams started this season with a 31-10 loss against the Buffalo Bills, they managed to comeback and win their second and third games against the Atlanta Falcons and the Arizona Cardinals.

The Rams have allowed their opponents to score 23.3 points per game this season. Their defense ranks 11th, contrasting with the 49ers' ranking in second in the league.

Cooper Kupp was the star of the Rams’ game against the Cardinals, scoring a touchdown and continuing to rack up receptions. He will be a key factor for the Rams in this game, as his connection with Matthew Stafford often determines whether or not the Rams will have a chance in a game.

The Rams are struggling with injuries this season. TE Daniel Hardy is out due to an ankle injury. The team will also lose Kyren Williams to a leg injury through early November.

San Francisco 49ers

The San Francisco 49ers are coming off of a loss in their last game, having fallen against the Denver Broncos on Sunday Night Football in Week 3. Despite their 1-2 start, losing two games to the Chicago Bears and the Denver Broncos, the 49ers' defense have only allowed their opponents to score 12.3 points per game. The team's defense allowed zero points during the first half of their game against the Seahawks, and had a similarly strong first half on defense against the Broncos.

Unfortunately, 49ers starting QB Trey Lance will be out for the season due to an ankle injury. OLB Azeez Al-Shaair and Offensive Tackle Trent Williams will also be absent until November due to ankle and knee injuries.

Gus Anderson
Gus Anderson is a gambling wizard. As a kid he dreamt about becoming a Tennis, Hockey and Golf professional but ended up as a gambling professional with focus on both sports & casino.