Indianapolis Colts vs Denver Broncos 10/6/2022 Prediction and DraftKings Sportsbook Promo

Last updated October 6, 2022

12:15 AM ET Oct 7
Indianapolis Colts vs Denver Broncos
Denver Broncos to WIN

The Denver Broncos will host the Indianapolis Colts for Thursday Night Football at Empower Field at Mile High. Both teams have been struggling this season over the past four games. The Colts are 1-2-1 after a defeat against the Tennessee Titans in Week 4.  Meanwhile, the Broncos are coming to this game following a 32-23 loss to the Las Vegas Raiders last week.

The Broncos are the moneyline favorite at -165 for this in Week 5 regular season game, according to the oddsmakers at DraftKings Sportsbook. If you want to participate in betting on this Indianapolis Colts vs Denver Broncos game, you can use DraftKings' Bet $5, Win $200 promotion to claim $200 in free bets if your $5 bet wins.

The Pick: Denver Broncos | Moneyline @ -165
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Why bet on the Denver Broncos?

✅The Indianapolis Colts defense has struggled this season with 21.3 allowed points per game, compared to 17.0 points per game allowed by the Broncos.
✅The Denver Broncos have better offensive stats with 16.5 points per game compared to the Colts' 14.3 points per game.
✅The Broncos are 2-0 in home games this season.

Teams: Indianapolis Colts vs Denver Broncos
When: Thursday, October 6, at 8:15 p.m. ET
Venue: Empower Field at Mile High, Denver, CO
Betting Pick: Denver Broncos to win | Moneyline @ -165

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Indianapolis Colts vs Denver Broncos

Indianapolis Colts

The Indianapolis Colts have seen better days after a disappointing start to their season. Indianapolis only managed to play to a tie against the Houston Texans in Week 1, then they suffered two consecutive losses against the Jacksonville Jaguars and the Tennessee Titans respectively. The Colts need to sort out their defensive performance after allowing 21.3 points per game, while their offense has only averaged 14.3 points per game.

Colts quarterback Matt Ryan finished the game against Tennessee with 27 completions in 37 pass attempts for 356 yards and two TDs. Through Week 4, Ryan has thrown five touchdowns for 1,125 passing yards with five interceptions.

Due to injury, the Colts are without RB Jonathan Taylor, LB Shaquille Leonard and DT Tyquan Lewis, while Julian Blackmon and Ryan Kelly are still questionable.

Denver Broncos

The Denver Broncos are trying to get back on the winning track following their loss against the Raiders last week. They are 2-2 so far this season.

Coach Nathaniel Hackett needs to improve the team's offensive performance as they have gained a total of 1,418 yards for 16.5 points per game, while the defense has allowed 17.0 points per game.

QB Russell Wilson has thrown four TDs and 980 yards so far this season. However, Wilson has shoulder soreness and is questionable to play in this upcoming game. Their ground game had been led by Javonte Williams with 204 rushing yards, but Williams has to sit out the remainder of the season after suffering a torn ACL during the game against the Raiders.

On the injury list, LB Jonathon Cooper, RB Melvin Gordon III and CB K'Waun Williams are questionable alongside LB Aaron Patrick who sustained a possible concussion following Sunday's loss at Allegiant Stadium.

Gus Anderson
Gus Anderson is a gambling wizard. As a kid he dreamt about becoming a Tennis, Hockey and Golf professional but ended up as a gambling professional with focus on both sports & casino.