Carolina Panthers vs. Buffalo Bills - DraftKings Sportsbook Promo and Prediction

Last updated August 25, 2022

12:00 PM ET Aug 26
Panthers vs. Bills
Panthers to WIN

On Friday night, the Buffalo Bills and the Carolina Panthers square off in Week 3 NFL preseason action at Bank of America Stadium.

The Buffalo Bills will look to build on their 42-15 preseason victory over the Denver Broncos to improve to 2-0. The victory was the result of a complete team effort, with Buffalo gaining 208 yards on 27 carries.

On the other side, the Panthers were not as fortunate last week. Despite a 3-0 lead after the first quarter for Matt Rhule's team, the New England Patriots dominated the rest of the game, defeating Carolina 20-10.

You can bet on any team to win the game with the Buffalo Moneyline at +200 or the Panthers at -240 at DraftKings Sportsbook. To make betting more exciting, you can place a $5 bet on any team, and DraftKings Sportsbook will pay you $200 if your pick wins.

The Pick: Panthers Moneyline @ -240
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Why bet on the Panthers?

✅ The Panthers are 1-1 in the preseason.
✅ Christian McCaffrey averages 67 yards per game on the ground this offseason.
✅ The Panthers are racking eight sacks in the preseason.

Teams: Carolina Panthers vs. Buffalo Bills 
When: Friday, August 26, 2022, at 7:00 p.m. ET
Venue: Bank of America Stadium, Charlotte, NC
Betting Pick: The Panthers to win Moneyline @ -240 

Bet on Carolina Panthers vs. Buffalo Bills with DraftKings Sportsbook

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Carolina Panthers vs. Buffalo Bills

Carolina Panthers 

The majority of the Panthers' starters did not play in last week's preseason game against the New England Patriots because head coach Matt Rhule wanted to give them a break after two hard joint practices.

P.J. Walker went 8-of-14 for 107 yards and gave away two interceptions in his last game against the Patriots. He was 0-for-2 on deep throws and fumbled in the end zone late for a Patriots defensive score.

With Ikem Ekwonu on his backside, there's more hope for Sam Darnold or Baker Mayfield to succeed, especially as Christian McCaffrey appeared to have recovered from his injuries.

For Friday’s game, the Panthers will have a slight advantage because they will most likely play more of their starters. The Bills' defense should keep things close, but Carolina's players have more on the line as they compete for a 53-man roster spot.

Corral tore the Lisfranc ligament during the match against New England and will be out for the season. Khalan Tolson was also waived with an unspecified injury, so he will not be joining the Panthers soon.

Buffalo Bills 

The Buffalo Bills are considered Super Bowl favorites heading into the 2022 NFL season. The time has come for this franchise to win its first Lombardi Trophy, with quarterback Josh Allen leading an impressive roster.

This preseason, the Bills have Raheem Blackshear who finished the team's last game with 58 rushing yards and an average of 11.6 yards per carry. He also had two receptions for 21 yards and a kickoff return for 21 yards.

Along with Blackshear, Duke Johnson had a strong game against the Denver Broncos. He finished the game with nine rushing attempts and was only three yards behind Blackshear for the team lead in rushing yards with 55.

The Bills management has placed Ike Boettger on the reserve list and will not play against the Panthers. Bills safety Jordan Poyer injured his elbow during a training camp practice and will miss the game too.

Jake Williams
Jake Williams is a sports gambling expert. He's been writing in the sports betting and DFS industry for over a decade. He specializes in MLB and NBA, along with College Basketball and College Football.